Just when you thought medical marijuana had gone up in smoke in Florida, here we go again.

After an amendment to legalize marijuana for medical use failed at the polls in 2014, the very same organizers are pushing to put a new amendment on the 2016 ballot, and they have already collected enough signatures to trigger an economic impact review.

That means state economists are meeting Wednesday in Tallahassee to come up with a projection for how much tax revenue might flow from the cultivation and sale of medical marijuana in Florida.

That figure, expected to be released later Wednesday, could be hundreds of millions of dollars, and if it's big enough, supporters hope that will galvanize even pot-neutral Floridians to vote for medical marijuana on the premise that it might mean more tax money for schools and roads.

Map showing the 23 U.S. states and Washington, D.C., have laws on the books legalizing medical marijuana